PLATELETS AND THROMBOPOIESIS Identifying drugs that cause acute thrombocytopenia: an analysis using 3 distinct methods
نویسندگان
چکیده
1Department of Biostatistics and Epidemiology, College of Public Health, The University of Oklahoma Health Sciences Center, Oklahoma City 2Pfizer, Inc, New York, NY; 3Department of Medicine, New York University School of Medicine, New York, NY; 4New York Medical College, Valhalla; 5Brunel University, West London, United Kingdom; 6University of Maryland College of Pharmacy, Baltimore; 7Department of Medicine, Medical College of Wisconsin, Milwaukee; 8Blood Research Institute, BloodCenter of Wisconsin, Milwaukee; and 9Department of Medicine, College of Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City
منابع مشابه
Differential Diagnosis of Thrombocytopenia in Hematopoietic Stem Cell Transplant Patients
Thrombocytopenia has remained a major concern in post-haematopoietic stem cell transplant patients. It is a strong negative indicator for survival and is often seen in patients with advanced acute and chronic Graft versus host disease (GVHD). The pathogenesis of thrombocytopenia varies from impaired thrombopoiesis to increased turnover of platelets. The dose of CD34+ cells and that of megakaryo...
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Thrombocytopenia is caused by disorders impairing platelet production, causing platelet destruction or leading to platelet sequestration. In addition, there are both congenital and acquired disorders of platelet function. These latter conditions may lead to the functional equivalent of thrombocytopenia, often despite the presence of a normal platelet count. Platelet transfusion represents an im...
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